Your Weekly Dose of Mycology Research
Single-atom nanozymes (SAzymes) are engineered enzyme mimics offering enhanced catalytic capabilities. This study introduces Ce-induced adaptive synergism, where a Ce atom activates Ni-Fe sites to enhance multi-enzymatic functions of Ce-MOF, showing potent antifungal effects against Fusarium solani and fostering beneficial microbial recovery, thereby supporting sustainable Panax ginseng cultivation.
Unspecific peroxygenases (UPOs) are versatile enzymes known for oxyfunctionalization, although their potential is underexplored compared to cytochrome P450s. Researchers have engineered Aspergillus niger's UPO for enantioselective α-hydroxylation of β-ketoesters, achieving up to 97% yield and >99:1 enantiomeric ratios, thus expanding UPOs' applicability in industrial biocatalysis.
This study employs fDOG, an advanced ortholog search tool, to analyze plant cell wall-degrading enzymes (PCDs) across 18,000 taxa, revealing unexpected genomic richness in certain invertebrates. Utilizing UMAP for data visualization, fDOG identifies noteworthy enzymatic repertoire shifts and potential contributions to the global carbon cycle, illustrating its effectiveness in mapping metabolic capacities across the tree of life.
Protein thermostability refers to a protein's capacity to maintain structure and function at varying temperatures, crucial for organismal thermotolerance. This study reveals that both structural and cellular environmental changes drive differences in thermostability between Saccharomyces species. Proteins in S. cerevisiae exhibit enhanced stability, largely mediated by amino acid substitutions, underscoring their evolutionary adaptation.