MycoWeekly Newsletter

Your Weekly Dose of Mycology Research

Pickering Emulsion Biocatalysis with Engineered Living Cells for Degrading Polycarbonate Plastics.

2025-05-24
Small • Level 3 (4 panels)
Shan Wang, Zhimin Gong, René Hübner, Henrik Karring, Changzhu Wu

In the study 'Pickering Emulsion Biocatalysis with Engineered Living Cells for Degrading Polycarbonate Plastics,' researchers introduce a biocompatible polymer coating that enhances the stability of Pickering emulsions—mixtures stabilized by solid particles—for 192 hours. This approach significantly improves the interaction between plastics and biocatalysts, offering a promising method for plastic waste remediation, and highlights the potential of engineered cell surfaces in environmental applications.

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Genome Mining of Isoindolinone-Containing Peptide Natural Products.

2025-05-19
Journal of the American Chemical Society • Level 3 (4 panels)
Yalong Zhang, Lin Wu, Zuwei Wang, Wenyu Han, Tyler A Kerr, Yi Tang

Isoindolinone-containing peptide natural products (PNPs) are compounds with potential therapeutic applications. This study highlights ATP-grasp enzymes and adenylate-forming enzyme-binding sites (ABSs) as promising targets for discovering new PNPs. The research emphasizes these enzymes' biocatalytic efficiency in forming amide bonds, paving the way for innovative fungal bioactive compound discovery.

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Ventriculitis characteristics and outcomes (VELCRO): an international retrospective cohort study

2025-05-20
Brain • Level 3 (13 panels)
David Luque Paz, Beatriz Díaz-Pollán, M. Boyer-Besseyre, F. Djanikian, A. Munier, Flávia Cunha, L. Escaut, Guillaume Martin-Blondel, B. Sarton, P. Jaquet, François Arrivé, Rémi Wolf, Vincent Legros, Mathieu Willig, O. Sipahi, Laure Flurin, Antoine Bianchi, B. Balança, Alejandro Díez-Vidal, Joshua Puel, B. Soyer, Rita Lino, Thibaut Leveque, Alexis Salomon, A. Serris, R. Larcher, Fabrice Bruneel, N. Mongardon, M. Martinot, A. Mazeraud, Michel Wolff, R. Sonneville, F. Valour, P. Tattevin, Alexis Salomon, P. Jaubert, Ivan Pelegrin, María Milagros Montero, P. Bailly, Thibaut Leveque, M. Martinot, N. Mongardon, Mathieu Willig, Rémi Wolf, O. Sipahi, Gamze Şanlıdağ Işbilen, F. Valour, Florian Contard, B. Balança, Pierre Goffin, M. Boyer-Besseyre, Beatriz Díaz-Pollán, Alejandro Díez-Vidal, Fernando Fernández Hinojal, Antoine Bianchi, F. Djanikian, Joshua Puel, L. Escaut, A. Herbrecht, Pierre Etienne Leblanc, Nicolas Fortineau, Laure Flurin, R. Sonneville, Sarah Benghanem, A. Munier, B. Soyer, A. Serris, Clémentine de La Porte des Vaux, Fanny Lanternier, A. Beurton, R. Larcher, Flávia Cunha, Rita Lino, Lurdes Santos, François Arrivé, Vincent Legros, François Eugène, David Luque Paz, P. Tattevin, M. Revest, P. Le Reste, P. Jaquet, Marco Seneghini, Werner Albrich, Mathilde Zenou, Baptiste Jean, B. Sarton, Guillaume Reiter, Delphine Dghayem, Fabrice Bonneville, Guillaume Martin-Blondel, Vanessa Jean-Michel, F. Reizine, Fabrice Bruneel

In the study 'Ventriculitis Characteristics and Outcomes (VELCRO)', researchers provide a current analysis of ventriculitis—an infection of brain ventricles often associated with fungi—examining its diverse causes and consequences. This international study identifies critical risk factors affecting 1-year all-cause mortality, offering insights relevant to fungal infections in neurological settings.

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Calcineurin controls the cytokinesis machinery during thermal stress in Cryptococcus deneoformans.

2025-05-21
Proceedings of the National Academy of Sciences of the United States of America • Level 3 (24 panels)
V. Yadav, Anna Floyd Averette, R. Upadhya, Joseph Heitman

In "Calcineurin controls the cytokinesis machinery during thermal stress in Cryptococcus deneoformans," researchers demonstrate that calcineurin, a crucial signaling molecule, orchestrates the cytokinesis machinery linked to the mitotic exit network under thermal stress conditions. This study underscores calcineurin's pivotal role in cellular division, particularly in stress adaptation, highlighting potential avenues for antifungal strategies.

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