MycoWeekly Newsletter

Your Weekly Dose of Mycology Research

ILC3s promote intestinal tuft cell hyperplasia and anthelmintic immunity through RANK signaling.

2025-05-16
Science immunology • Level 3 (11 panels)
Hongkai Xu, Yibo Wang, Wenyan Wang, Yangbo Fu, Ju Qiu, Yan Shi, Lei Yuan, Chen Dong, Xiaoyu Hu, Ye-Guang Chen, Xiaohuan Guo

Innate lymphoid cells (ILC3s) are immune cells involved in mucosal defense and homeostasis. A recent study reveals that helminth infections reprogram ILC3s to enhance anthelmintic immunity. These cells are crucial for protection against helminths by regulating intestinal tuft cell hyperplasia and type 2 immunity. This highlights a novel mechanism linking ILC3 activity and intestinal defense.

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Distribution of haploid chromosomes into separate nuclei in two pathogenic fungi.

2025-05-15
Science • Level 3 (24 panels)
Yan Xu, Lei Tian, Jinyi Tan, Weijie Huang, Josh Li, Nigel O'Neil, Martin Hirst, Phil Hieter, Yuelin Zhang, Xin Li

This study investigates haploid chromosome distribution in pathogenic fungi Sclerotinia sclerotiorum and Botrytis cinerea. Unlike typical haploid cells containing a full set of chromosomes per nucleus, these fungi show a unique cellular organization where each nucleus houses only a subset of haploid chromosomes. This finding suggests a novel genetic mechanism with implications for understanding fungal pathogenicity.

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Assessment of the phytopathogen Cladosporium cladosporioides inhibition by Meyerozyma guilliermondii LMA-Cp01 using isothermal microcalorimetry.

2025-05-15
Mycologia • Level 2 (6 panels)
Leonardo Covarrubias-Rivera, J. A. Ragazzo-Sánchez, M. Calderón‐Santoyo

Isothermal microcalorimetry (IMC), a method for measuring thermal changes in microbial activity, was employed to evaluate the efficacy of Meyerozyma guilliermondii LMA-Cp01 against the phytopathogen Cladosporium cladosporioides. The study reveals a strong correlation between total heat output and in vitro inhibition, validating IMC as an effective complement to traditional fungal inhibition assays.

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Multigene-based establishment of a novel Pleosporales family (Leandriaceae) and neotypification of Leandria momordicae Rangel.

2025-05-14
Mycologia • Level 2 (6 panels)
Maria Isabella de Souza Feitosa, L. Boiteux, Maria Esther de Noronha Fonseca, Josiene Silva Veloso, D. Pinho, M. P. Câmara, A. Reis

The study "Multigene-based establishment of a novel Pleosporales family (Leandriaceae) and neotypification of Leandria momordicae Rangel" underscores the recognition of understudied fungal diversity within Neotropical regions. Utilizing multigene phylogenetic analysis, researchers identified the new family Leandriaceae and have defined a neotype for Leandria momordicae, highlighting significant taxonomic advancements in Pleosporales.

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